Pharmacokinetics and Pharmacodynamics

Discuss the difference between pharmacokinetics and pharmacodynamics.

Discuss the metabolism, absorption, bioavailability, and excretion.

Give an example of how each can be impacted (medical condition, body habitus, route of administration, etc.)
Discuss half-life elimination and influences that can alter it.

Please respond to two of your peers. Responses should involve at least one reference and move the conversation forward.